Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost‐effective manufacturing processes. Microcarriers enable the culture of anchorage‐dependent cells in stirred‐tank bioreactors. However, no robust, transferable methodology for microcarrier selection exist...

Descripción completa

Detalles Bibliográficos
Autores principales: Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Hewitt, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991290/
https://www.ncbi.nlm.nih.gov/pubmed/26632496
http://dx.doi.org/10.1002/biot.201400862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991290/
https://www.ncbi.nlm.nih.gov/pubmed/26632496
http://dx.doi.org/10.1002/biot.201400862

Ejemplares similares