Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease

Patients who suffer from autoinflammatory disease (AID) exhibit seemingly uncontrolled release of interleukin (IL)-1β. The presence of this inflammatory cytokine triggers immune activation in absence of pathogens and foreign material. The mechanisms that contribute to ‘sterile inflammation’ episodes...

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Detalles Bibliográficos
Autores principales: van der Burgh, Robert, Meeldijk, Jan, Jongeneel, Lieneke, Frenkel, Joost, Bovenschen, Niels, van Gijn, Mariëlle, Boes, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991381/
https://www.ncbi.nlm.nih.gov/pubmed/26992230
http://dx.doi.org/10.18632/oncotarget.8086

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