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5-Fluorouracil targets thymidylate synthase in the selective suppression of T(H)17 cell differentiation
While it is well established that treatment of cancer patients with 5-Fluorouracil (5-FU) can result in immune suppression, the exact function of 5-FU in the modulation of immune cells has not been fully established. We found that low dose 5-FU selectively suppresses T(H)17 and T(H)1 cell differenti...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991385/ https://www.ncbi.nlm.nih.gov/pubmed/27027355 http://dx.doi.org/10.18632/oncotarget.8344 |