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Development of interleukin-17-producing Vγ2(+) γδ T cells is reduced by ICOS signaling in the thymus

Co-stimulation is an integral part of T cell signaling involved in almost all facets of T cell biology. While much is known about co-stimulation in differentiation and function of conventional αβ T cells, less is known about how co-stimulation affects the development and programming of γδ T cells. I...

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Detalles Bibliográficos
Autores principales: Buus, Terkild Brink, Schmidt, Jonas Damgård, Bonefeld, Charlotte Menné, Geisler, Carsten, Lauritsen, Jens Peter Holst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991387/
https://www.ncbi.nlm.nih.gov/pubmed/27235509
http://dx.doi.org/10.18632/oncotarget.8464

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