Cargando…

The role of N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applications

Changes in glycosylation, which is one of the most common protein post-translational modifications, are considered to be a hallmark of cancer. N-glycans can modulate cell migration, cell-cell adhesion, cell signaling, growth and metastasis. The colorectal cancer (CRC) is a leading cause of cancer-re...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Freitas Junior, Julio Cesar Madureira, Morgado-Díaz, José Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991391/ https://www.ncbi.nlm.nih.gov/pubmed/26539643 http://dx.doi.org/10.18632/oncotarget.6283

Ejemplares similares

Insulin/IGF-I Signaling Pathways Enhances Tumor Cell Invasion through Bisecting GlcNAc N-glycans Modulation. An Interplay with E-Cadherin
por: de-Freitas-Junior, Julio Cesar Madureira, et al.
Publicado: (2013)

Glycans as Regulatory Elements of the Insulin/IGF System: Impact in Cancer Progression
por: de-Freitas-Junior, Julio Cesar M., et al.
Publicado: (2017)

IL-17 Triggers Invasive and Migratory Properties in Human MSCs, while IFNy Favors their Immunosuppressive Capabilities: Implications for the “Licensing” Process
por: Du-Rocher, Bárbara, et al.
Publicado: (2020)

IgG N-glycan Signatures as Potential Diagnostic and Prognostic Biomarkers
por: Haslund-Gourley, Benjamin S., et al.
Publicado: (2023)

Plasma N-glycans in colorectal cancer risk
por: Doherty, Margaret, et al.
Publicado: (2018)

High-Mannose N-Glycans as Malignant Progression Markers in Early-Stage Colorectal Cancer
por: Boyaval, Fanny, et al.
Publicado: (2022)

Discovery of N-glycan Biomarkers for the Canine Osteoarthritis
por: Lee, Hyunjun, et al.
Publicado: (2020)

Serum N-glycan profiling is a potential biomarker for castration-resistant prostate cancer
por: Matsumoto, Teppei, et al.
Publicado: (2019)

Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells
por: DE ALBUQUERQUE-XAVIER, ANA CRISTINA, et al.
Publicado: (2012)

Fucosylated N-glycans as early biomarkers of COVID-19 severity
por: Paton, Beatrix, et al.
Publicado: (2023)

Recent Progress in Chemo-Enzymatic Methods for the Synthesis of N-Glycans
por: Chao, Qiang, et al.
Publicado: (2020)

Nanoparticle Biomolecular Corona-Based Enrichment of Plasma Glycoproteins for N-Glycan Profiling and Application in Biomarker Discovery
por: Trinh, Duong N., et al.
Publicado: (2022)

Healthy human serum N-glycan profiling reveals the influence of ethnic variation on the identified cancer-relevant glycan biomarkers
por: Gebrehiwot, Abrha G., et al.
Publicado: (2018)

The Identification and Characterization of Novel N-glycan-based Biomarkers in Gastric Cancer
por: Liu, Long, et al.
Publicado: (2013)

Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer
por: Tsai, Kuei-Yen, et al.
Publicado: (2023)

N-glycosylation and receptor tyrosine kinase signaling affect claudin-3 levels in colorectal cancer cells
por: Pérez, Amelia G., et al.
Publicado: (2020)

Glycan–protein interactions determine kinetics of N-glycan remodeling
por: Mathew, Corina, et al.
Publicado: (2021)

Glycans as Biomarkers in Prostate Cancer
por: Scott, Emma, et al.
Publicado: (2019)

Glycosylation Alterations in Cancer Cells, Prognostic Value of Glycan Biomarkers and Their Potential as Novel Therapeutic Targets in Breast Cancer
por: Peric, Luka, et al.
Publicado: (2022)

Epithelial‐Mesenchymal Transition in colorectal cancer: Annexin A2 is caught in the crosshairs
por: ROCHA, Murilo Ramos, et al.
Publicado: (2021)

Glycan analysis of therapeutic glycoproteins
por: Zhang, Lei, et al.
Publicado: (2015)

Claudin-3 Overexpression Increases the Malignant Potential of Colorectal Cancer Cells: Roles of ERK1/2 and PI3K-Akt as Modulators of EGFR signaling
por: de Souza, Waldemir F., et al.
Publicado: (2013)

Serum N‐glycan profiling as a diagnostic biomarker for the identification and assessment of psoriasis
por: Zou, Chengyun, et al.
Publicado: (2021)

N‐glycan signature of serum immunoglobulins as a diagnostic biomarker of urothelial carcinomas
por: Kodama, Hirotake, et al.
Publicado: (2021)

GlycanAnalyzer: software for automated interpretation of N-glycan profiles after exoglycosidase digestions
por: Walsh, Ian, et al.
Publicado: (2019)

GlycanAnalyzer: software for automated interpretation of N-glycan profiles after exoglycosidase digestions
por: Walsh, Ian, et al.
Publicado: (2019)

Helminth Glycans at the Host-Parasite Interface and Their Potential for Developing Novel Therapeutics
por: Bunte, Myrna J. M., et al.
Publicado: (2022)

Glycan Analysis as Biomarkers for Testicular Cancer
por: Hires, Michal, et al.
Publicado: (2019)

Systematic synthesis of bisected N-glycans and unique recognitions by glycan-binding proteins
por: Cao, Xuefeng, et al.
Publicado: (2022)

Comparison of denaturing agent effects in enzymatic N-glycan release for human plasma N-glycan analysis
por: KAYILI, H. Mehmet, et al.
Publicado: (2022)

Serum N-Glycans: A New Diagnostic Biomarker for Light Chain Multiple Myeloma
por: Chen, Jie, et al.
Publicado: (2015)

Serum IgG N-glycans act as novel serum biomarkers of ankylosing spondylitis
por: Wang, Jingrong, et al.
Publicado: (2019)

IgG1 Fc N-glycan galactosylation as a biomarker for immune activation
por: de Jong, Sanne E., et al.
Publicado: (2016)

Plant N-glycan breakdown by human gut Bacteroides
por: Crouch, Lucy I., et al.
Publicado: (2022)

CSF N-Glycan Profiles to Investigate Biomarkers in Brain Developmental Disorders: Application to Leukodystrophies Related to eIF2B Mutations
por: Fogli, Anne, et al.
Publicado: (2012)

Glycans and Glycan-Binding Proteins as Regulators and Potential Targets in Leukocyte Recruitment
por: Krautter, Franziska, et al.
Publicado: (2021)

So You Discovered a Potential Glycan-Based Biomarker; Now What? We Developed a High-Throughput Method for Quantitative Clinical Glycan Biomarker Validation
por: Shipman, Joshua T., et al.
Publicado: (2020)

T cell senescence by N-glycan branching
por: Mkhikian, Haik, et al.
Publicado: (2022)

N-glycan breakdown by bacterial CAZymes
por: Crouch, Lucy I.
Publicado: (2023)

Glycomic Approach for Potential Biomarkers on Prostate Cancer: Profiling of N-Linked Glycans in Human Sera and pRNS Cell Lines
por: de Leoz, Maria Lorna A., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_8g1h4mv4hc4hmitc9aufasodv2