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Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors
Histone lysine acetylation is an epigenetic mark regulated by histone acetyltransferases and histone deacetylases (HDAC) which plays an important role in tumorigenesis. In this study, we observed a strong overexpression of class IIa HDAC9, at the mRNA and protein levels, in the most aggressive human...
Autores principales: | Lapierre, Marion, Linares, Aurélien, Dalvai, Mathieu, Duraffourd, Céline, Bonnet, Sandrine, Boulahtouf, Abdelhay, Rodriguez, Carmen, Jalaguier, Stéphan, Assou, Said, Orsetti, Beatrice, Balaguer, Patrick, Maudelonde, Thierry, Blache, Philippe, Bystricky, Kerstin, Boulle, Nathalie, Cavaillès, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991412/ https://www.ncbi.nlm.nih.gov/pubmed/26930713 http://dx.doi.org/10.18632/oncotarget.7564 |
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