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Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells

The metastatic cascade describes the escape of primary tumour cells to distant secondary sites. Cells at the leading tumour edge are thought to undergo epithelial-mesenchymal transition (EMT), to enhance their motility and invasion for spreading. Whether EMT cells directly promote tumour angiogenesi...

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Detalles Bibliográficos
Autores principales:	Gopal, Shashi K., Greening, David W., Hanssen, Eric G., Zhu, Hong-Jian, Simpson, Richard J., Mathias, Rommel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991413/ https://www.ncbi.nlm.nih.gov/pubmed/26919098 http://dx.doi.org/10.18632/oncotarget.7573

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