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Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network

To better understand how the apoptosis repressor with caspase recruitment domain (ARC) protein confers drug resistance in acute myeloid leukemia (AML), we investigated the role of ARC in regulating leukemia-mesenchymal stromal cell (MSC) interactions. In addition to the previously reported effect on...

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Detalles Bibliográficos
Autores principales: Carter, Bing Z., Mak, Po Yee, Chen, Ye, Mak, Duncan H., Mu, Hong, Jacamo, Rodrigo, Ruvolo, Vivian, Arold, Stefan T., Ladbury, John E., Burks, Jared K., Kornblau, Steven, Andreeff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991438/
https://www.ncbi.nlm.nih.gov/pubmed/26956049
http://dx.doi.org/10.18632/oncotarget.7911