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Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network
To better understand how the apoptosis repressor with caspase recruitment domain (ARC) protein confers drug resistance in acute myeloid leukemia (AML), we investigated the role of ARC in regulating leukemia-mesenchymal stromal cell (MSC) interactions. In addition to the previously reported effect on...
Autores principales: | Carter, Bing Z., Mak, Po Yee, Chen, Ye, Mak, Duncan H., Mu, Hong, Jacamo, Rodrigo, Ruvolo, Vivian, Arold, Stefan T., Ladbury, John E., Burks, Jared K., Kornblau, Steven, Andreeff, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991438/ https://www.ncbi.nlm.nih.gov/pubmed/26956049 http://dx.doi.org/10.18632/oncotarget.7911 |
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