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Survival kinase genes present prognostic significance in glioblastoma

Cancer biomarkers with a strong predictive power for diagnosis/prognosis and a potential to be therapeutic targets have not yet been fully established. Here we employed a loss-of-function screen in glioblastoma (GBM), an infiltrative brain tumor with a dismal prognosis, and identified 20 survival ki...

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Detalles Bibliográficos
Autores principales: Varghese, Robin T., Liang, Yanping, Guan, Ting, Franck, Christopher T., Kelly, Deborah F., Sheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991443/
https://www.ncbi.nlm.nih.gov/pubmed/26956052
http://dx.doi.org/10.18632/oncotarget.7917