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Insulin receptor substrate 1 is a substrate of the Pim protein kinases

The Pim family of serine/threonine protein kinases (Pim 1, 2, and 3) contribute to cellular transformation by regulating glucose metabolism, protein synthesis, and mitochondrial oxidative phosphorylation. Drugs targeting the Pim protein kinases are being tested in phase I/II clinical trials for the...

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Detalles Bibliográficos
Autores principales: Song, Jin H., Padi, Sathish K. R., Luevano, Libia A., Minden, Mark D., DeAngelo, Daniel J., Hardiman, Gary, Ball, Lauren E., Warfel, Noel A., Kraft, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991444/
https://www.ncbi.nlm.nih.gov/pubmed/26956053
http://dx.doi.org/10.18632/oncotarget.7918