Cargando…

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome

PURPOSE: 25% of all lung cancer cases are neuroendocrine (NELC) including typical (TC) and atypical carcinoid (AC), large-cell neuroendocrine (LCNEC) and small cell lung cancer (SCLC). Prognostic and predictive biomarkers are lacking. EXPERIMENTAL DESIGN: Sixty patients were used for nCounter mRNA e...

Descripción completa

Detalles Bibliográficos
Autores principales: Henry Walter, Robert Fred, Mairinger, Fabian Dominik, Werner, Robert, Vollbrecht, Claudia, Hager, Thomas, Schmid, Kurt Werner, Wohlschlaeger, Jeremias, Christoph, Daniel Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991445/
https://www.ncbi.nlm.nih.gov/pubmed/27064343
http://dx.doi.org/10.18632/oncotarget.7737