Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway

It has been reported that there are multiple mechanisms by which bufalin could exert its antimetastatic effect. HIF-1α has been reported to be involved in tumor migration and invasion by regulating EMT. However, it is not known whether bufalin could exert the antimetastatic effect by modulating HIF-...

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Detalles Bibliográficos
Autores principales: Wang, Haiyong, Zhang, Chenyue, Xu, Litao, Zang, Kun, Ning, Zhouyu, Jiang, Feng, Chi, Huiying, Zhu, Xiaoyan, Meng, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991447/
https://www.ncbi.nlm.nih.gov/pubmed/26958938
http://dx.doi.org/10.18632/oncotarget.7935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991447/
https://www.ncbi.nlm.nih.gov/pubmed/26958938
http://dx.doi.org/10.18632/oncotarget.7935

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