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Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway
It has been reported that there are multiple mechanisms by which bufalin could exert its antimetastatic effect. HIF-1α has been reported to be involved in tumor migration and invasion by regulating EMT. However, it is not known whether bufalin could exert the antimetastatic effect by modulating HIF-...
Autores principales: | Wang, Haiyong, Zhang, Chenyue, Xu, Litao, Zang, Kun, Ning, Zhouyu, Jiang, Feng, Chi, Huiying, Zhu, Xiaoyan, Meng, Zhiqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991447/ https://www.ncbi.nlm.nih.gov/pubmed/26958938 http://dx.doi.org/10.18632/oncotarget.7935 |
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