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Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells

Porcine circovirus type 2 (PCV2) is the primary cause of porcine circovirus disease, and ochratoxin A (OTA)-induced oxidative stress promotes PCV2 replication. In humans, selenoprotein S (SelS) has antioxidant ability, but it is unclear whether SelS affects viral infection. Here, we stably transfect...

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Detalles Bibliográficos
Autores principales:	Gan, Fang, Hu, Zhihua, Huang, Yu, Xue, Hongxia, Huang, Da, Qian, Gang, Hu, Junfa, Chen, Xingxiang, Wang, Tian, Huang, Kehe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991468/ https://www.ncbi.nlm.nih.gov/pubmed/26943035 http://dx.doi.org/10.18632/oncotarget.7814

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