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The complement receptor 3 (CD11b/CD18) agonist Leukadherin‐1 suppresses human innate inflammatory signalling

Complement receptor 3 (CR3, CD11b/CD18) is a multi‐functional receptor expressed predominantly on myeloid and natural killer (NK) cells. The R77H variant of CD11b, encoded by the ITGAM rs1143679 polymorphism, is associated robustly with development of the autoimmune disease systemic lupus erythemato...

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Detalles Bibliográficos
Autores principales: Roberts, A. L., Fürnrohr, B. G., Vyse, T. J., Rhodes, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991522/
https://www.ncbi.nlm.nih.gov/pubmed/27118513
http://dx.doi.org/10.1111/cei.12803