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Development of a Full-Thickness Human Gingiva Equivalent Constructed from Immortalized Keratinocytes and Fibroblasts

Organotypic models make it possible to investigate the unique properties of oral mucosa in vitro. For gingiva, the use of human primary keratinocytes (KC) and fibroblasts (Fib) is limited due to the availability and size of donor biopsies. The use of physiologically relevant immortalized cell lines...

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Detalles Bibliográficos
Autores principales: Buskermolen, Jeroen K., Reijnders, Christianne M.A., Spiekstra, Sander W., Steinberg, Thorsten, Kleverlaan, Cornelis J., Feilzer, Albert J., Bakker, Astrid D., Gibbs, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991602/
https://www.ncbi.nlm.nih.gov/pubmed/27406216
http://dx.doi.org/10.1089/ten.tec.2016.0066