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Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence

The transcription factor hepatocyte nuclear factor 1β (HNF1β) is ubiquitously overexpressed in ovarian clear cell carcinoma (CCC) and is a potential therapeutic target. To explore potential approaches that block HNF1β transcription we have identified and characterised extensively the nuclear localis...

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Detalles Bibliográficos
Autores principales:	Wiedmann, Mareike M., Aibara, Shintaro, Spring, David R., Stewart, Murray, Brenton, James D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991853/ https://www.ncbi.nlm.nih.gov/pubmed/27346421 http://dx.doi.org/10.1016/j.jsb.2016.06.018

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