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Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes

Partial remission in patients newly diagnosed with type 1 diabetes is a period of good glucose control that can last from several weeks to over a year. The clinical significance of the remission period is that patients might be more responsive to immunotherapy if treated within this period. This art...

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Detalles Bibliográficos
Autores principales: Narsale, Aditi, Moya, Rosita, Robertson, Hannah Kathryn, Davies, Joanna Davida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992037/
https://www.ncbi.nlm.nih.gov/pubmed/27579340
http://dx.doi.org/10.1016/j.dib.2016.07.059
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author Narsale, Aditi
Moya, Rosita
Robertson, Hannah Kathryn
Davies, Joanna Davida
author_facet Narsale, Aditi
Moya, Rosita
Robertson, Hannah Kathryn
Davies, Joanna Davida
author_sort Narsale, Aditi
collection PubMed
description Partial remission in patients newly diagnosed with type 1 diabetes is a period of good glucose control that can last from several weeks to over a year. The clinical significance of the remission period is that patients might be more responsive to immunotherapy if treated within this period. This article provides clinical data that indicates the level of glucose control and insulin-secreting β-cell function of each patient in the study at baseline (within 3 months of diagnosis), and at 3, 6, 9, 12, 18 and 24 months post-baseline. The relative frequency of immune cell subsets in the PBMC of each patient and the association between the frequency of immune cell subsets measured and length of remission is also shown. These data support the findings reported in the accompanying publication, “A pilot study showing associations between frequency of CD4+ memory cell subsets at diagnosis and duration of partial remission in type 1 diabetes” (Moya et al., 2016) [1], where a full interpretation, including biological relevance of the study can be found.
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spelling pubmed-49920372016-08-30 Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes Narsale, Aditi Moya, Rosita Robertson, Hannah Kathryn Davies, Joanna Davida Data Brief Data Article Partial remission in patients newly diagnosed with type 1 diabetes is a period of good glucose control that can last from several weeks to over a year. The clinical significance of the remission period is that patients might be more responsive to immunotherapy if treated within this period. This article provides clinical data that indicates the level of glucose control and insulin-secreting β-cell function of each patient in the study at baseline (within 3 months of diagnosis), and at 3, 6, 9, 12, 18 and 24 months post-baseline. The relative frequency of immune cell subsets in the PBMC of each patient and the association between the frequency of immune cell subsets measured and length of remission is also shown. These data support the findings reported in the accompanying publication, “A pilot study showing associations between frequency of CD4+ memory cell subsets at diagnosis and duration of partial remission in type 1 diabetes” (Moya et al., 2016) [1], where a full interpretation, including biological relevance of the study can be found. Elsevier 2016-08-06 /pmc/articles/PMC4992037/ /pubmed/27579340 http://dx.doi.org/10.1016/j.dib.2016.07.059 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Narsale, Aditi
Moya, Rosita
Robertson, Hannah Kathryn
Davies, Joanna Davida
Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes
title Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes
title_full Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes
title_fullStr Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes
title_full_unstemmed Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes
title_short Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes
title_sort data on correlations between t cell subset frequencies and length of partial remission in type 1 diabetes
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992037/
https://www.ncbi.nlm.nih.gov/pubmed/27579340
http://dx.doi.org/10.1016/j.dib.2016.07.059
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