The role of sirtuins in cellular homeostasis

Sirtuins are evolutionarily conserved nicotinamide adenine dinucleotide (NAD(+))-dependent lysine deacylases or ADP-ribosyltransferases. These cellular enzymes are metabolic sensors sensitive to NAD(+) levels that maintain physiological homeostasis in the animal and plant cells.

Detalles Bibliográficos
Autores principales: Kupis, Wioleta, Pałyga, Jan, Tomal, Ewa, Niewiadomska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992043/
https://www.ncbi.nlm.nih.gov/pubmed/27154583
http://dx.doi.org/10.1007/s13105-016-0492-6
Descripción
Sumario:Sirtuins are evolutionarily conserved nicotinamide adenine dinucleotide (NAD(+))-dependent lysine deacylases or ADP-ribosyltransferases. These cellular enzymes are metabolic sensors sensitive to NAD(+) levels that maintain physiological homeostasis in the animal and plant cells.

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