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The role of sirtuins in cellular homeostasis
Sirtuins are evolutionarily conserved nicotinamide adenine dinucleotide (NAD(+))-dependent lysine deacylases or ADP-ribosyltransferases. These cellular enzymes are metabolic sensors sensitive to NAD(+) levels that maintain physiological homeostasis in the animal and plant cells.
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992043/ https://www.ncbi.nlm.nih.gov/pubmed/27154583 http://dx.doi.org/10.1007/s13105-016-0492-6 |
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author | Kupis, Wioleta Pałyga, Jan Tomal, Ewa Niewiadomska, Ewa |
author_facet | Kupis, Wioleta Pałyga, Jan Tomal, Ewa Niewiadomska, Ewa |
author_sort | Kupis, Wioleta |
collection | PubMed |
description | Sirtuins are evolutionarily conserved nicotinamide adenine dinucleotide (NAD(+))-dependent lysine deacylases or ADP-ribosyltransferases. These cellular enzymes are metabolic sensors sensitive to NAD(+) levels that maintain physiological homeostasis in the animal and plant cells. |
format | Online Article Text |
id | pubmed-4992043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-49920432016-09-06 The role of sirtuins in cellular homeostasis Kupis, Wioleta Pałyga, Jan Tomal, Ewa Niewiadomska, Ewa J Physiol Biochem Mini Review Sirtuins are evolutionarily conserved nicotinamide adenine dinucleotide (NAD(+))-dependent lysine deacylases or ADP-ribosyltransferases. These cellular enzymes are metabolic sensors sensitive to NAD(+) levels that maintain physiological homeostasis in the animal and plant cells. Springer Netherlands 2016-05-06 2016 /pmc/articles/PMC4992043/ /pubmed/27154583 http://dx.doi.org/10.1007/s13105-016-0492-6 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Mini Review Kupis, Wioleta Pałyga, Jan Tomal, Ewa Niewiadomska, Ewa The role of sirtuins in cellular homeostasis |
title | The role of sirtuins in cellular homeostasis |
title_full | The role of sirtuins in cellular homeostasis |
title_fullStr | The role of sirtuins in cellular homeostasis |
title_full_unstemmed | The role of sirtuins in cellular homeostasis |
title_short | The role of sirtuins in cellular homeostasis |
title_sort | role of sirtuins in cellular homeostasis |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992043/ https://www.ncbi.nlm.nih.gov/pubmed/27154583 http://dx.doi.org/10.1007/s13105-016-0492-6 |
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