Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism

Fucosyltransferase 2 (FUT2) is an enzyme that is responsible for the synthesis of the H antigen in body fluids and on the intestinal mucosa. The H antigen is an oligosaccharide moiety that acts as both an attachment site and carbon source for intestinal bacteria. Non-secretors, who are homozygous fo...

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Detalles Bibliográficos
Autores principales: Tong, Maomeng, McHardy, Ian, Ruegger, Paul, Goudarzi, Maryam, Kashyap, Purna C, Haritunians, Talin, Li, Xiaoxiao, Graeber, Thomas G, Schwager, Emma, Huttenhower, Curtis, Fornace, Albert J, Sonnenburg, Justin L, McGovern, Dermot PB, Borneman, James, Braun, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992076/
https://www.ncbi.nlm.nih.gov/pubmed/24781901
http://dx.doi.org/10.1038/ismej.2014.64

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