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Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia
Chemotherapy remains a mainstay of cancer treatment but its use is often limited by the development of adverse reactions. Severe loss of body weight (cachexia) is a frequent cause of death in cancer patients and is exacerbated by chemotherapy. We show that genetic inactivation of vascular endothelia...
Autores principales: | Klose, Ralph, Krzywinska, Ewelina, Castells, Magali, Gotthardt, Dagmar, Putz, Eva Maria, Kantari-Mimoun, Chahrazade, Chikdene, Naima, Meinecke, Anna-Katharina, Schrödter, Katrin, Helfrich, Iris, Fandrey, Joachim, Sexl, Veronika, Stockmann, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992172/ https://www.ncbi.nlm.nih.gov/pubmed/27538380 http://dx.doi.org/10.1038/ncomms12528 |
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