Cargando…

Highly active promoters and native secretion signals for protein production during extremely low growth rates in Aspergillus niger

BACKGROUND: The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch cultivation. An alternative technique is continuous cultivation, which promises improved yield and optimized pipeline efficiency. RESUL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wanka, Franziska, Arentshorst, Mark, Cairns, Timothy C., Jørgensen, Thomas, Ram, Arthur F. J., Meyer, Vera
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992228/ https://www.ncbi.nlm.nih.gov/pubmed/27544686 http://dx.doi.org/10.1186/s12934-016-0543-2

Ejemplares similares

The transcriptomic fingerprint of glucoamylase over-expression in Aspergillus niger
por: Kwon, Min Jin, et al.
Publicado: (2012)

Engineering of Aspergillus niger for the production of secondary metabolites
por: Richter, Lennart, et al.
Publicado: (2014)

The Transcriptomic Signature of RacA Activation and Inactivation Provides New Insights into the Morphogenetic Network of Aspergillus niger
por: Kwon, Min Jin, et al.
Publicado: (2013)

Correction: The Transcriptomic Signature of RacA Activation and Inactivation Provides New Insights into the Morphogenetic Network of Aspergillus niger
por: Kwon, Min Jin, et al.
Publicado: (2014)

Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in Aspergillus niger
por: Cairns, Timothy C., et al.
Publicado: (2023)

Conditional Expression of the Small GTPase ArfA Impacts Secretion, Morphology, Growth, and Actin Ring Position in Aspergillus niger
por: Fiedler, Markus R. M., et al.
Publicado: (2018)

A new vector for efficient gene targeting to the pyrG locus in Aspergillus niger
por: Arentshorst, Mark, et al.
Publicado: (2015)

Something old, something new: challenges and developments in Aspergillus niger biotechnology
por: Cairns, Timothy C., et al.
Publicado: (2021)

Improving cellulase production by Aspergillus niger using adaptive evolution
por: Patyshakuliyeva, Aleksandrina, et al.
Publicado: (2016)

How a fungus shapes biotechnology: 100 years of Aspergillus niger research
por: Cairns, Timothy C., et al.
Publicado: (2018)

Functional analysis of the protocatechuate branch of the β-ketoadipate pathway in Aspergillus niger
por: Sgro, Michael, et al.
Publicado: (2023)

Effects of a defective ERAD pathway on growth and heterologous protein production in Aspergillus niger
por: Carvalho, Neuza D. S. P., et al.
Publicado: (2010)

Quantitative phenotypic screens of Aspergillus niger mutants in solid and liquid culture
por: Cairns, Timothy, et al.
Publicado: (2022)

Construction of an improved Aspergillus niger platform for enhanced glucoamylase secretion
por: Fiedler, Markus R. M., et al.
Publicado: (2018)

The carbon starvation response of Aspergillus niger during submerged cultivation: Insights from the transcriptome and secretome
por: Nitsche, Benjamin M, et al.
Publicado: (2012)

A set of isogenic auxotrophic strains for constructing multiple gene deletion mutants and parasexual crossings in Aspergillus niger
por: Niu, Jing, et al.
Publicado: (2016)

A Library of Aspergillus niger Chassis Strains for Morphology Engineering Connects Strain Fitness and Filamentous Growth With Submerged Macromorphology
por: Cairns, Timothy C., et al.
Publicado: (2022)

Mutations in AraR leading to constitutive of arabinolytic genes in Aspergillus niger under derepressing conditions
por: Reijngoud, Jos, et al.
Publicado: (2019)

Functional analysis of three putative galactofuranosyltransferases with redundant functions in galactofuranosylation in Aspergillus niger
por: Arentshorst, Mark, et al.
Publicado: (2019)

Interrogation of the cell wall integrity pathway in Aspergillus niger identifies a putative negative regulator of transcription involved in chitin deposition
por: van Leeuwe, Tim M., et al.
Publicado: (2020)

Polycistronic gene expression in Aspergillus niger
por: Schuetze, Tabea, et al.
Publicado: (2017)

Transcriptomic and molecular genetic analysis of the cell wall salvage response of Aspergillus niger to the absence of galactofuranose synthesis
por: Park, Joohae, et al.
Publicado: (2016)

Genetic Characterization of Mutations Related to Conidiophore Stalk Length Development in Aspergillus niger Laboratory Strain N402
por: Demirci, Ebru, et al.
Publicado: (2021)

Natural Variation and the Role of Zn(2)Cys(6) Transcription Factors SdrA, WarA and WarB in Sorbic Acid Resistance of Aspergillus niger
por: Seekles, Sjoerd J., et al.
Publicado: (2022)

Colony growth and biofilm formation of Aspergillus niger under simulated microgravity
por: Cortesão, Marta, et al.
Publicado: (2022)

Inducer-independent production of pectinases in Aspergillus niger by overexpression of the D-galacturonic acid-responsive transcription factor gaaR
por: Alazi, Ebru, et al.
Publicado: (2018)

A community-driven reconstruction of the Aspergillus niger metabolic network
por: Brandl, Julian, et al.
Publicado: (2018)

Protocol for gene characterization in Aspergillus niger using 5S rRNA-CRISPR-Cas9-mediated Tet-on inducible promoter exchange
por: Zheng, Xiaomei, et al.
Publicado: (2022)

The FlbA-regulated predicted transcription factor Fum21 of Aspergillus niger is involved in fumonisin production
por: Aerts, David, et al.
Publicado: (2017)

Loss of function of the carbon catabolite repressor CreA leads to low but inducer‐independent expression from the feruloyl esterase B promoter in Aspergillus niger
por: Reijngoud, Jos, et al.
Publicado: (2021)

Aspergillus niger Secretes Citrate to Increase Iron Bioavailability
por: Odoni, Dorett I., et al.
Publicado: (2017)

Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress
por: Carvalho, Neuza DSP, et al.
Publicado: (2012)

W361R mutation in GaaR, the regulator of D‐galacturonic acid‐responsive genes, leads to constitutive production of pectinases in Aspergillus niger
por: Alazi, Ebru, et al.
Publicado: (2018)

Comprehensively dissecting the hub regulation of PkaC on high‐productivity and pellet macromorphology in citric acid producing Aspergillus niger
por: Zheng, Xiaomei, et al.
Publicado: (2022)

Aspergillus niger Spores Are Highly Resistant to Space Radiation
por: Cortesão, Marta, et al.
Publicado: (2020)

Functional exploration of co-expression networks identifies a nexus for modulating protein and citric acid titres in Aspergillus niger submerged culture
por: Cairns, Timothy C., et al.
Publicado: (2019)

Autophagy is dispensable to overcome ER stress in the filamentous fungus Aspergillus niger
por: Burggraaf, Anne‐Marie, et al.
Publicado: (2016)

Correction to: Functional exploration of co-expression networks identifies a nexus for modulating protein and citric acid titres in Aspergillus niger submerged culture
por: Cairns, Timothy C., et al.
Publicado: (2019)

Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway
por: Jørgensen, Thomas R, et al.
Publicado: (2009)

Heterogeneity in liquid shaken cultures of Aspergillus niger inoculated with melanised conidia or conidia of pigmentation mutants
por: van Veluw, G.J., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_q9s9vsqvsiqr78llij6v2sk2ga