Cargando…

Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis

BACKGROUND: Malignant thymomas are rarely associated with bone metastasis and T-cell lymphocytosis. CASE PRESENTATION: A 47–year-old female patient was admitted to our hospital for ptosis. A diagnosis of malignant thymoma was made based on the thymectomy and pathological result. Peripheral T-cell ly...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Luo, Zhou, Xi, Li, Zheng, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992230/
https://www.ncbi.nlm.nih.gov/pubmed/27542926
http://dx.doi.org/10.1186/s12893-016-0171-0
_version_ 1782448979314737152
author Zhao, Luo
Zhou, Xi
Li, Zheng
Liu, Yong
author_facet Zhao, Luo
Zhou, Xi
Li, Zheng
Liu, Yong
author_sort Zhao, Luo
collection PubMed
description BACKGROUND: Malignant thymomas are rarely associated with bone metastasis and T-cell lymphocytosis. CASE PRESENTATION: A 47–year-old female patient was admitted to our hospital for ptosis. A diagnosis of malignant thymoma was made based on the thymectomy and pathological result. Peripheral T-cell lymphocytosis and bone metastasis were found later. T-cell lymphocytosis was relived after surgical and radiation therapy to the metastasis. CONCLUSION: Peripheral T-cell lymphocytosis is a rare paraneoplastic phenomenon associated with thymomas. This report is the first to describe an invasive thymoma with late bone metastasis accompanied with T-cell lymphocytosis. We should be aware of peripheral T-cell lymphocytosis in thymomas and it may contribute to a better understanding of the complex physiology and pathogenesis of thymoma.
format Online
Article
Text
id pubmed-4992230
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-49922302016-08-21 Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis Zhao, Luo Zhou, Xi Li, Zheng Liu, Yong BMC Surg Case Report BACKGROUND: Malignant thymomas are rarely associated with bone metastasis and T-cell lymphocytosis. CASE PRESENTATION: A 47–year-old female patient was admitted to our hospital for ptosis. A diagnosis of malignant thymoma was made based on the thymectomy and pathological result. Peripheral T-cell lymphocytosis and bone metastasis were found later. T-cell lymphocytosis was relived after surgical and radiation therapy to the metastasis. CONCLUSION: Peripheral T-cell lymphocytosis is a rare paraneoplastic phenomenon associated with thymomas. This report is the first to describe an invasive thymoma with late bone metastasis accompanied with T-cell lymphocytosis. We should be aware of peripheral T-cell lymphocytosis in thymomas and it may contribute to a better understanding of the complex physiology and pathogenesis of thymoma. BioMed Central 2016-08-19 /pmc/articles/PMC4992230/ /pubmed/27542926 http://dx.doi.org/10.1186/s12893-016-0171-0 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Zhao, Luo
Zhou, Xi
Li, Zheng
Liu, Yong
Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
title Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
title_full Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
title_fullStr Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
title_full_unstemmed Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
title_short Bone metastasis of malignant thymomas associated with peripheral T-cell lymphocytosis
title_sort bone metastasis of malignant thymomas associated with peripheral t-cell lymphocytosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992230/
https://www.ncbi.nlm.nih.gov/pubmed/27542926
http://dx.doi.org/10.1186/s12893-016-0171-0
work_keys_str_mv AT zhaoluo bonemetastasisofmalignantthymomasassociatedwithperipheraltcelllymphocytosis
AT zhouxi bonemetastasisofmalignantthymomasassociatedwithperipheraltcelllymphocytosis
AT lizheng bonemetastasisofmalignantthymomasassociatedwithperipheraltcelllymphocytosis
AT liuyong bonemetastasisofmalignantthymomasassociatedwithperipheraltcelllymphocytosis