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The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17

Biliary atresia, the most common indication for pediatric liver transplantation, is a fibrotic disease of unknown etiology affecting the extrahepatic bile ducts of newborns. The recently described toxin biliatresone causes lumen obstruction in mouse cholangiocyte spheroids and represents a new model...

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Detalles Bibliográficos
Autores principales:	Waisbourd‐Zinman, Orith, Koh, Hong, Tsai, Shannon, Lavrut, Pierre‐Marie, Dang, Christine, Zhao, Xiao, Pack, Michael, Cave, Jeff, Hawes, Mark, Koo, Kyung A., Porter, John R., Wells, Rebecca G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Autoimmune, Cholestatic and Biliary Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992464/ https://www.ncbi.nlm.nih.gov/pubmed/27081925 http://dx.doi.org/10.1002/hep.28599

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