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Novel Findings into AIRE Genetics and Functioning: Clinical Implications

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), formerly known as autoimmune polyendocrine syndrome type 1, is a paradigm of a monogenic autoimmune disease caused by mutations of a gene, named autoimmune regulator (AIRE). AIRE acts as a transcription regulator that promotes...

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Detalles Bibliográficos
Autores principales:	De Martino, Lucia, Capalbo, Donatella, Improda, Nicola, Lorello, Paola, Ungaro, Carla, Di Mase, Raffaella, Cirillo, Emilia, Pignata, Claudio, Salerno, Mariacarolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992815/ https://www.ncbi.nlm.nih.gov/pubmed/27597936 http://dx.doi.org/10.3389/fped.2016.00086

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