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Filtrating colorectal cancer associated genes by integrated analyses of global DNA methylation and hydroxymethylation in cancer and normal tissue
Recently, 5-hydroxymethylcytosine patterning across the tumor genome was considered as a hallmark of cancer development and progression. However, locus-specific difference of hydroxymethylation between colorectal cancer and normal tissue is unknown. In this study, we performed a newly developed meth...
Autores principales: | Li, Ming, Gao, Fei, Xia, Yudong, Tang, Yi, Zhao, Wei, Jin, Congcong, Luo, Huijuan, Wang, Junwen, Li, Qingshu, Wang, Yalan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992821/ https://www.ncbi.nlm.nih.gov/pubmed/27546520 http://dx.doi.org/10.1038/srep31826 |
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