Cargando…

Identification of cellular senescence-specific genes by comparative transcriptomics

Cellular senescence is defined as permanent cell cycle arrest induced by various stresses. Although the p53 transcriptional activity is essential for senescence induction, the downstream genes that are crucial for senescence remain unsolved. Here, by using a developed experimental system in which ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nagano, Taiki, Nakano, Masayuki, Nakashima, Akio, Onishi, Kengo, Yamao, Shunsuke, Enari, Masato, Kikkawa, Ushio, Kamada, Shinji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992837/ https://www.ncbi.nlm.nih.gov/pubmed/27545311 http://dx.doi.org/10.1038/srep31758

Ejemplares similares

Branched-Chain Amino Acids Enhance Premature Senescence through Mammalian Target of Rapamycin Complex I-Mediated Upregulation of p21 Protein
por: Nakano, Masayuki, et al.
Publicado: (2013)

d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species
por: Nagano, Taiki, et al.
Publicado: (2019)

LY6D-induced macropinocytosis as a survival mechanism of senescent cells
por: Nagano, Taiki, et al.
Publicado: (2020)

Fission yeast arrestin-related trafficking adaptor, Arn1/Any1, is ubiquitinated by Pub1 E3 ligase and regulates endocytosis of Cat1 amino acid transporter
por: Nakashima, Akio, et al.
Publicado: (2014)

Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family
por: Kawai, Masaaki, et al.
Publicado: (2015)

Riboflavin transporter SLC52A1, a target of p53, suppresses cellular senescence by activating mitochondrial complex II
por: Nagano, Taiki, et al.
Publicado: (2021)

Contribution of Caspase(s) to the Cell Cycle Regulation at Mitotic Phase
por: Hashimoto, Toshiaki, et al.
Publicado: (2011)

The S. pombe CDK5 Orthologue Pef1 Cooperates with Three Cyclins, Clg1, Pas1 and Psl1, to Promote Pre-Meiotic DNA Replication
por: Matsuda, Shinya, et al.
Publicado: (2021)

Preferential Fas-mediated apoptotic execution at G(1) phase: the resistance of mitotic cells to the cell death
por: Hashimoto, T, et al.
Publicado: (2012)

The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast
por: Ma, Ning, et al.
Publicado: (2016)

Transcriptomic Analysis of Cellular Senescence: One Step Closer to Senescence Atlas
por: Kim, Sohee, et al.
Publicado: (2021)

Identification of Regions Critical for the Integrity of the TSC1-TSC2-TBC1D7 Complex
por: Santiago Lima, Arthur Jorge, et al.
Publicado: (2014)

The Yeast Tor Signaling Pathway Is Involved in G2/M Transition via Polo-Kinase
por: Nakashima, Akio, et al.
Publicado: (2008)

Cellular Senescence and Aging in Myotonic Dystrophy
por: Hasuike, Yuhei, et al.
Publicado: (2022)

RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth
por: Kano, Takuya, et al.
Publicado: (2021)

Association of CAD, a multifunctional protein involved in pyrimidine synthesis, with mLST8, a component of the mTOR complexes
por: Nakashima, Akio, et al.
Publicado: (2013)

Markers of cellular senescence. Telomere shortening as a marker of cellular senescence
por: Bernadotte, Alexandra, et al.
Publicado: (2016)

Cellular senescence in cancer
por: Kim, Young Hwa, et al.
Publicado: (2019)

On the evolution of cellular senescence
por: Kowald, Axel, et al.
Publicado: (2020)

Identification and validation of biomarkers based on cellular senescence in mild cognitive impairment
por: Ma, Songmei, et al.
Publicado: (2023)

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing
por: Voutetakis, Konstantinos, et al.
Publicado: (2015)

Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic Alterations
por: Kwiatkowska, Katarzyna Malgorzata, et al.
Publicado: (2023)

Cellular senescence and chromatin organisation
por: Narita, M
Publicado: (2007)

Never-ageing cellular senescence
por: Ogrunc, Müge, et al.
Publicado: (2011)

Four faces of cellular senescence
por: Rodier, Francis, et al.
Publicado: (2011)

Probing the depths of cellular senescence
por: Baker, Darren J., et al.
Publicado: (2013)

Cellular Senescence, Aging and Cancer
por: Campisi, Judith
Publicado: (2001)

Juxtacrine regulation of cellular senescence
por: Narita, Masashi
Publicado: (2019)

Mitochondrial Homeostasis and Cellular Senescence
por: Vasileiou, Panagiotis V.S., et al.
Publicado: (2019)

Cellular senescence in osteoarthritis pathology
por: McCulloch, Kendal, et al.
Publicado: (2017)

Lipid Players of Cellular Senescence
por: Millner, Alec, et al.
Publicado: (2020)

Cellular Senescence in Arterial Diseases
por: Shimizu, Ippei, et al.
Publicado: (2020)

Cellular Senescence in Neurodegenerative Diseases
por: Martínez-Cué, Carmen, et al.
Publicado: (2020)

Cellular Senescence and Mammalian Healthspan
por: Campisi, Judith
Publicado: (2020)

Cellular Senescence in Brain Aging
por: Sikora, Ewa, et al.
Publicado: (2021)

Epigenetic Regulation of Cellular Senescence
por: Crouch, Jack, et al.
Publicado: (2022)

Lipids as Regulators of Cellular Senescence
por: Hamsanathan, Shruthi, et al.
Publicado: (2022)

Mechanisms and Regulation of Cellular Senescence
por: Roger, Lauréline, et al.
Publicado: (2021)

Altered endocytosis in cellular senescence
por: Shin, Eun-Young, et al.
Publicado: (2021)

Cellular Senescence in Lung Fibrosis
por: Hernandez-Gonzalez, Fernanda, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_429ek2bnk1sr6jbu127a6v10is