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Effect of MDR1 gene polymorphisms on mortality in paraquat intoxicated patients

Paraquat is a fatal herbicide following acute exposure. Previous studies have suggested that multidrug resistance protein 1 (MDR1) might help remove paraquat from the lungs and the kidney. MDR1 single-nucleotide polymorphisms (SNPs) are involved in the pharmacokinetics of many drugs. The purpose of...

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Detalles Bibliográficos
Autores principales: Kim, Hak Jae, Kim, Hyung-Ki, Kwon, Jun-Tack, Lee, Sun-hyo, el Park, Sam, Gil, Hyo-Wook, Song, Ho-yeon, Hong, Sae-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992846/
https://www.ncbi.nlm.nih.gov/pubmed/27545861
http://dx.doi.org/10.1038/srep31765