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CAPS1 stabilizes the state of readily releasable synaptic vesicles to fusion competence at CA3–CA1 synapses in adult hippocampus

Calcium-dependent activator protein for secretion 1 (CAPS1) regulates exocytosis of dense-core vesicles in neuroendocrine cells and of synaptic vesicles in neurons. However, the synaptic function of CAPS1 in the mature brain is unclear because Caps1 knockout (KO) results in neonatal death. Here, usi...

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Detalles Bibliográficos
Autores principales: Shinoda, Yo, Ishii, Chiaki, Fukazawa, Yugo, Sadakata, Tetsushi, Ishii, Yuki, Sano, Yoshitake, Iwasato, Takuji, Itohara, Shigeyoshi, Furuichi, Teiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992871/
https://www.ncbi.nlm.nih.gov/pubmed/27545744
http://dx.doi.org/10.1038/srep31540

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