Drug induced exfoliative dermatitis: state of the art

Drug induced exfoliative dermatitis (ED) are a group of rare and severe drug hypersensitivity reactions (DHR) involving skin and usually occurring from days to several weeks after drug exposure. Erythema multiforme (EM), Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the mai...

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Autores principales: Yacoub, Mona-Rita, Berti, Alvise, Campochiaro, Corrado, Tombetti, Enrico, Ramirez, Giuseppe Alvise, Nico, Andrea, Di Leo, Elisabetta, Fantini, Paola, Sabbadini, Maria Grazia, Nettis, Eustachio, Colombo, Giselda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993006/
https://www.ncbi.nlm.nih.gov/pubmed/27551239
http://dx.doi.org/10.1186/s12948-016-0045-0
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author Yacoub, Mona-Rita
Berti, Alvise
Campochiaro, Corrado
Tombetti, Enrico
Ramirez, Giuseppe Alvise
Nico, Andrea
Di Leo, Elisabetta
Fantini, Paola
Sabbadini, Maria Grazia
Nettis, Eustachio
Colombo, Giselda
author_facet Yacoub, Mona-Rita
Berti, Alvise
Campochiaro, Corrado
Tombetti, Enrico
Ramirez, Giuseppe Alvise
Nico, Andrea
Di Leo, Elisabetta
Fantini, Paola
Sabbadini, Maria Grazia
Nettis, Eustachio
Colombo, Giselda
author_sort Yacoub, Mona-Rita
collection PubMed
description Drug induced exfoliative dermatitis (ED) are a group of rare and severe drug hypersensitivity reactions (DHR) involving skin and usually occurring from days to several weeks after drug exposure. Erythema multiforme (EM), Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the main clinical presentations of drug induced ED. Overall, T cells are the central player of these immune-mediated drug reactions. Here we provide a systematic review on frequency, risk factors, pathogenesis, clinical features and management of patients with drug induced ED. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12948-016-0045-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-49930062016-08-23 Drug induced exfoliative dermatitis: state of the art Yacoub, Mona-Rita Berti, Alvise Campochiaro, Corrado Tombetti, Enrico Ramirez, Giuseppe Alvise Nico, Andrea Di Leo, Elisabetta Fantini, Paola Sabbadini, Maria Grazia Nettis, Eustachio Colombo, Giselda Clin Mol Allergy Review Drug induced exfoliative dermatitis (ED) are a group of rare and severe drug hypersensitivity reactions (DHR) involving skin and usually occurring from days to several weeks after drug exposure. Erythema multiforme (EM), Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the main clinical presentations of drug induced ED. Overall, T cells are the central player of these immune-mediated drug reactions. Here we provide a systematic review on frequency, risk factors, pathogenesis, clinical features and management of patients with drug induced ED. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12948-016-0045-0) contains supplementary material, which is available to authorized users. BioMed Central 2016-08-22 /pmc/articles/PMC4993006/ /pubmed/27551239 http://dx.doi.org/10.1186/s12948-016-0045-0 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Yacoub, Mona-Rita
Berti, Alvise
Campochiaro, Corrado
Tombetti, Enrico
Ramirez, Giuseppe Alvise
Nico, Andrea
Di Leo, Elisabetta
Fantini, Paola
Sabbadini, Maria Grazia
Nettis, Eustachio
Colombo, Giselda
Drug induced exfoliative dermatitis: state of the art
title Drug induced exfoliative dermatitis: state of the art
title_full Drug induced exfoliative dermatitis: state of the art
title_fullStr Drug induced exfoliative dermatitis: state of the art
title_full_unstemmed Drug induced exfoliative dermatitis: state of the art
title_short Drug induced exfoliative dermatitis: state of the art
title_sort drug induced exfoliative dermatitis: state of the art
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993006/
https://www.ncbi.nlm.nih.gov/pubmed/27551239
http://dx.doi.org/10.1186/s12948-016-0045-0
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