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Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling

We previously demonstrated PAR2 starts upstreamed with tissue factor (TF) and factor VII (FVII), inhibited autophagy via mTOR signaling in HCC. However, the mechanism underlying for merging functions of PAR2 with the coagulation system in HCC progression remained unclear. The present study aimed to...

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Detalles Bibliográficos
Autores principales: Tsai, M-C, Chen, K-D, Wang, C-C, Huang, K-T, Wu, C-H, Kuo, I-Y, Chen, L-Y, Hu, T-H, Goto, S, Nakano, T, Dorling, A, McVey, J H, Chen, C-L, Lin, C-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993037/
https://www.ncbi.nlm.nih.gov/pubmed/27551480
http://dx.doi.org/10.1038/cddiscovery.2015.51