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Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling
We previously demonstrated PAR2 starts upstreamed with tissue factor (TF) and factor VII (FVII), inhibited autophagy via mTOR signaling in HCC. However, the mechanism underlying for merging functions of PAR2 with the coagulation system in HCC progression remained unclear. The present study aimed to...
Autores principales: | Tsai, M-C, Chen, K-D, Wang, C-C, Huang, K-T, Wu, C-H, Kuo, I-Y, Chen, L-Y, Hu, T-H, Goto, S, Nakano, T, Dorling, A, McVey, J H, Chen, C-L, Lin, C-C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993037/ https://www.ncbi.nlm.nih.gov/pubmed/27551480 http://dx.doi.org/10.1038/cddiscovery.2015.51 |
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