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Reversal of intramyocellular lipid accumulation by lipophagy and a p62-mediated pathway

We have previously observed the reversal of lipid droplet deposition in skeletal muscle of morbidly obese patients following bariatric surgery. We now investigated whether activation of autophagy is the mechanism underlying this observation. For this purpose, we incubated rat L6 myocytes over a peri...

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Detalles Bibliográficos
Autores principales:	Lam, T, Harmancey, R, Vasquez, H, Gilbert, B, Patel, N, Hariharan, V, Lee, A, Covey, M, Taegtmeyer, H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993124/ https://www.ncbi.nlm.nih.gov/pubmed/27625792 http://dx.doi.org/10.1038/cddiscovery.2016.61

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