New vaccines: challenges of discovery

Vaccines have been a major component of preventing and controlling infectious diseases. The basis for discovery of what protects is reviewed as well as new attempts in utilizing Reverse Vaccinology, RNA‐RNA methods and proteome analysis are adding significantly to our knowledge. The challenge of how...

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Detalles Bibliográficos
Autor principal: Mahmoud, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Special Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993171/
https://www.ncbi.nlm.nih.gov/pubmed/27534704
http://dx.doi.org/10.1111/1751-7915.12397
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author Mahmoud, Adel
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description Vaccines have been a major component of preventing and controlling infectious diseases. The basis for discovery of what protects is reviewed as well as new attempts in utilizing Reverse Vaccinology, RNA‐RNA methods and proteome analysis are adding significantly to our knowledge. The challenge of how to define protective and defined components of microbes is still hampering efforts to discover new vaccines. Recent excitement about immunotherapy of cancer opens the way to develop vaccines against multiple malignancies.
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spelling pubmed-49931712016-08-31 New vaccines: challenges of discovery Mahmoud, Adel Microb Biotechnol Special Issue Articles Vaccines have been a major component of preventing and controlling infectious diseases. The basis for discovery of what protects is reviewed as well as new attempts in utilizing Reverse Vaccinology, RNA‐RNA methods and proteome analysis are adding significantly to our knowledge. The challenge of how to define protective and defined components of microbes is still hampering efforts to discover new vaccines. Recent excitement about immunotherapy of cancer opens the way to develop vaccines against multiple malignancies. John Wiley and Sons Inc. 2016-08-18 /pmc/articles/PMC4993171/ /pubmed/27534704 http://dx.doi.org/10.1111/1751-7915.12397 Text en © 2016 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Issue Articles
Mahmoud, Adel
New vaccines: challenges of discovery
title New vaccines: challenges of discovery
title_full New vaccines: challenges of discovery
title_fullStr New vaccines: challenges of discovery
title_full_unstemmed New vaccines: challenges of discovery
title_short New vaccines: challenges of discovery
title_sort new vaccines: challenges of discovery
topic Special Issue Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993171/
https://www.ncbi.nlm.nih.gov/pubmed/27534704
http://dx.doi.org/10.1111/1751-7915.12397
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