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Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery

Guanidinylated poly(amido amine)s with multiple disulfide linkages (Gua-SS-PAAs) were designed and constructed as nonviral gene carriers. The main chains of these novel carriers were synthesized based on monomers containing guanidino groups (guanidine hydrochloride and chlorhexidine), which could av...

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Detalles Bibliográficos
Autores principales: Yu, Jiankun, Zhang, Jinmin, Xing, Haonan, Yang, Zhen, Cai, Cuifang, Zhang, Conglu, Zhao, Xiaoyun, Wei, Minjie, Yang, Li, Ding, Pingtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993266/
https://www.ncbi.nlm.nih.gov/pubmed/27574429
http://dx.doi.org/10.2147/IJN.S109406