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Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery
Guanidinylated poly(amido amine)s with multiple disulfide linkages (Gua-SS-PAAs) were designed and constructed as nonviral gene carriers. The main chains of these novel carriers were synthesized based on monomers containing guanidino groups (guanidine hydrochloride and chlorhexidine), which could av...
Autores principales: | Yu, Jiankun, Zhang, Jinmin, Xing, Haonan, Yang, Zhen, Cai, Cuifang, Zhang, Conglu, Zhao, Xiaoyun, Wei, Minjie, Yang, Li, Ding, Pingtian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993266/ https://www.ncbi.nlm.nih.gov/pubmed/27574429 http://dx.doi.org/10.2147/IJN.S109406 |
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