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Evolutionary perspectives of telomerase RNA structure and function
Telomerase is the eukaryotic solution to the ‘end-replication problem’ of linear chromosomes by synthesising the highly repetitive DNA constituent of telomeres, the nucleoprotein cap that protects chromosome termini. Functioning as a ribonucleoprotein (RNP) enzyme, telomerase is minimally composed o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993307/ https://www.ncbi.nlm.nih.gov/pubmed/27359343 http://dx.doi.org/10.1080/15476286.2016.1205768 |