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Evolutionary perspectives of telomerase RNA structure and function

Telomerase is the eukaryotic solution to the ‘end-replication problem’ of linear chromosomes by synthesising the highly repetitive DNA constituent of telomeres, the nucleoprotein cap that protects chromosome termini. Functioning as a ribonucleoprotein (RNP) enzyme, telomerase is minimally composed o...

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Detalles Bibliográficos
Autores principales:	Podlevsky, Joshua D., Chen, Julian J.-L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993307/ https://www.ncbi.nlm.nih.gov/pubmed/27359343 http://dx.doi.org/10.1080/15476286.2016.1205768

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