Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Bacterial resistance to traditional antibiotics has driven research attempts to identify new drug targets in recently discovered regulatory pathways. Regulatory systems that utilize intracellular cyclic di-GMP (c-di-GMP) as a second messenger are one such class of target. c-di-GMP is a signaling mol...

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Detalles Bibliográficos
Autores principales: Rugjee, Kushal N., An, Shi-qi, Ryan, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993316/
https://www.ncbi.nlm.nih.gov/pubmed/27404278
http://dx.doi.org/10.3791/54115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993316/
https://www.ncbi.nlm.nih.gov/pubmed/27404278
http://dx.doi.org/10.3791/54115

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