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Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses

Senescent cells secrete senescence-associated secretory phenotype (SASP) proteins to carry out several functions, such as sensitizing surrounding cells to senesce; immunomodulation; impairing or fostering cancer growth; and promoting tissue development. Identifying secreted factors that achieve such...

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Detalles Bibliográficos
Autores principales: Özcan, Servet, Alessio, Nicola, Acar, Mustafa B., Mert, Eda, Omerli, Fatih, Peluso, Gianfranco, Galderisi, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993333/
https://www.ncbi.nlm.nih.gov/pubmed/27288264
http://dx.doi.org/10.18632/aging.100971