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EBV Nuclear Antigen 3C Mediates Regulation of E2F6 to Inhibit E2F1 Transcription and Promote Cell Proliferation

Epstein–Barr virus (EBV) is considered a ubiquitous herpesvirus with the ability to cause latent infection in humans worldwide. EBV-association is evidently linked to different types of human malignancies, mainly of epithelial and lymphoid origin. Of interest is the EBV nuclear antigen 3C (EBNA3C) w...

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Detalles Bibliográficos
Autores principales: Pei, Yonggang, Banerjee, Shuvomoy, Sun, Zhiguo, Jha, Hem Chandra, Saha, Abhik, Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993364/
https://www.ncbi.nlm.nih.gov/pubmed/27548379
http://dx.doi.org/10.1371/journal.ppat.1005844