Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells

Rickettsia (R.) typhi is the causative agent of endemic typhus, an emerging febrile disease that is associated with complications such as pneumonia, encephalitis and liver dysfunction. To elucidate how innate immune mechanisms contribute to defense and pathology we here analyzed R. typhi infection o...

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Detalles Bibliográficos
Autores principales: Papp, Stefanie, Moderzynski, Kristin, Rauch, Jessica, Heine, Liza, Kuehl, Svenja, Richardt, Ulricke, Mueller, Heidelinde, Fleischer, Bernhard, Osterloh, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993389/
https://www.ncbi.nlm.nih.gov/pubmed/27548618
http://dx.doi.org/10.1371/journal.pntd.0004935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993389/
https://www.ncbi.nlm.nih.gov/pubmed/27548618
http://dx.doi.org/10.1371/journal.pntd.0004935

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