Cargando…

Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells

Rickettsia (R.) typhi is the causative agent of endemic typhus, an emerging febrile disease that is associated with complications such as pneumonia, encephalitis and liver dysfunction. To elucidate how innate immune mechanisms contribute to defense and pathology we here analyzed R. typhi infection o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Papp, Stefanie, Moderzynski, Kristin, Rauch, Jessica, Heine, Liza, Kuehl, Svenja, Richardt, Ulricke, Mueller, Heidelinde, Fleischer, Bernhard, Osterloh, Anke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993389/ https://www.ncbi.nlm.nih.gov/pubmed/27548618 http://dx.doi.org/10.1371/journal.pntd.0004935

Ejemplares similares

CD4(+) T Cells Are as Protective as CD8(+) T Cells against Rickettsia typhi Infection by Activating Macrophage Bactericidal Activity
por: Moderzynski, Kristin, et al.
Publicado: (2016)

Cytotoxic effector functions of T cells are not required for protective immunity against fatal Rickettsia typhi infection in a murine model of infection: Role of T(H)1 and T(H)17 cytokines in protection and pathology
por: Moderzynski, Kristin, et al.
Publicado: (2017)

GroEL is an immunodominant surface-exposed antigen of Rickettsia typhi
por: Rauch, Jessica, et al.
Publicado: (2021)

GFPuv-Expressing Recombinant Rickettsia typhi: a Useful Tool for the Study of Pathogenesis and CD8(+) T Cell Immunology in R. typhi Infection
por: Hauptmann, Matthias, et al.
Publicado: (2017)

The neglected challenge: Vaccination against rickettsiae
por: Osterloh, Anke
Publicado: (2020)

Rickettsia typhi and Haemophagocytic Syndrome
por: Iaria, Chiara, et al.
Publicado: (2017)

Vaccine Design and Vaccination Strategies against Rickettsiae
por: Osterloh, Anke
Publicado: (2021)

Genetic typing of isolates of Rickettsia typhi
por: Kato, Cecilia Y., et al.
Publicado: (2022)

Immune response against rickettsiae: lessons from murine infection models
por: Osterloh, Anke
Publicado: (2017)

Serological evidence of exposure to Rickettsia felis and Rickettsia typhi in Australian veterinarians
por: Teoh, Yen Thon, et al.
Publicado: (2017)

Isolation of Rickettsia typhi from Human, Mexico
por: Zavala-Castro, Jorge E., et al.
Publicado: (2014)

Serosurveillance of Orientia tsutsugamushi and Rickettsia typhi in Bangladesh
por: Maude, Rapeephan R., et al.
Publicado: (2014)

Molecular Detection of Rickettsia typhi in Cats and Fleas
por: Nogueras, Maria Mercedes, et al.
Publicado: (2013)

Rickettsia typhi infection presenting as severe ARDS
por: Tran, Liem T., et al.
Publicado: (2019)

Rickettsia typhi central nervous system infection
por: Talhelm, Collin F., et al.
Publicado: (2020)

Severe Rickettsia typhi Infections, Costa Rica
por: Chinchilla, Diana, et al.
Publicado: (2023)

Rickettsia typhi as Cause of Fatal Encephalitic Typhus in Hospitalized Patients, Hamburg, Germany, 1940–1944
por: Rauch, Jessica, et al.
Publicado: (2018)

Rickettsia typhi infection in severe fever with thrombocytopenia patients, China
por: Zhang, Shao-Fei, et al.
Publicado: (2019)

Detection of Rickettsia felis, Rickettsia typhi, Bartonella Species and Yersinia pestis in Fleas (Siphonaptera) from Africa
por: Leulmi, Hamza, et al.
Publicado: (2014)

Case of Rickettsia typhi-induced Brain Abscess Mimicking Brain Tumor
por: Jang, Yoonhyuk, et al.
Publicado: (2018)

Rickettsia typhi and R. felis in Rat Fleas (Xenopsylla cheopis), Oahu, Hawaii
por: Eremeeva, Marina E., et al.
Publicado: (2008)

Development of Recombinase Polymerase Amplification Assays for Detection of Orientia tsutsugamushi or Rickettsia typhi
por: Chao, Chien-Chung, et al.
Publicado: (2015)

Direct evidence of Rickettsia typhi infection in Rhipicephalus sanguineus ticks and their canine hosts
por: Dzul-Rosado, Karla, et al.
Publicado: (2017)

The temporal dynamics of humoral immunity to Rickettsia typhi infection in murine typhus patients
por: Phakhounthong, K., et al.
Publicado: (2020)

Abducens nerve palsy with associated retinal involvement secondary to rickettsia typhi infection
por: Abderrahim, Kaies, et al.
Publicado: (2021)

Genome-wide screen for temperature-regulated genes of the obligate intracellular bacterium, Rickettsia typhi
por: Dreher-Lesnick, Sheila M, et al.
Publicado: (2008)

Rickettsia typhi Possesses Phospholipase A(2) Enzymes that Are Involved in Infection of Host Cells
por: Rahman, M. Sayeedur, et al.
Publicado: (2013)

Surface Proteome Analysis and Characterization of Surface Cell Antigen (Sca) or Autotransporter Family of Rickettsia typhi
por: Sears, Khandra T., et al.
Publicado: (2012)

The Cat Flea (Ctenocephalides felis) Immune Deficiency Signaling Pathway Regulates Rickettsia typhi Infection
por: Rennoll, Sherri A., et al.
Publicado: (2017)

Serosurvey of IgG Antibodies against Bartonella henselae and Rickettsia typhi in the Population of Attica, Greece
por: Dougas, Georgios, et al.
Publicado: (2020)

Successful Detection of Unrecognized Rickettsia typhi in Pregnancy Using Cell-Free Next-Generation Sequencing
por: Stafford, Irene A., et al.
Publicado: (2020)

Risk1, a Phosphatidylinositol 3-Kinase Effector, Promotes Rickettsia typhi Intracellular Survival
por: Voss, Oliver H., et al.
Publicado: (2020)

Seroprevalence of Orientia tsutsugamushi and Rickettsia typhi in water buffaloes (Bubalus bubalis) from Southern Thailand
por: Pangjai, Decha, et al.
Publicado: (2023)

Survey of rodent-borne pathogens in Singapore reveals the circulation of Leptospira spp., Seoul hantavirus, and Rickettsia typhi
por: Griffiths, Jane, et al.
Publicado: (2022)

Dose-response model of murine typhus (Rickettsia typhi): time post inoculation and host age dependency analysis
por: Tamrakar, Sushil B, et al.
Publicado: (2012)

Loop-Mediated Isothermal Amplification for Rickettsia typhi (the Causal Agent of Murine Typhus): Problems with Diagnosis at the Limit of Detection
por: Dittrich, Sabine, et al.
Publicado: (2014)

Rickettsia typhi IN RODENTS AND R. felis IN FLEAS IN YUCATÁN AS A POSSIBLE CAUSAL AGENT OF UNDEFINED FEBRILE CASES
por: PENICHE-LARA, Gaspar, et al.
Publicado: (2015)

RalF-Mediated Activation of Arf6 Controls Rickettsia typhi Invasion by Co-Opting Phosphoinositol Metabolism
por: Rennoll-Bankert, Kristen E., et al.
Publicado: (2016)

Two cases of uveitis associated with severe transaminitis during a Rickettsia typhi outbreak in Los Angeles County
por: Situ, Betty A., et al.
Publicado: (2020)

Oxford Nanopore MinION Sequencing Enables Rapid Whole Genome Assembly of Rickettsia typhi in a Resource-Limited Setting
por: Elliott, Ivo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5n3qgqvp70tlig10ammsaj6se4