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Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment
The precise localization and controlled chemical treatment of structures on a surface are significant challenges for common laboratory technologies. Herein, we introduce a microfluidic-based technology, employing a double-layer microfluidic device, which can trap and localize in situ and ex situ syn...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993413/ https://www.ncbi.nlm.nih.gov/pubmed/27500740 http://dx.doi.org/10.3791/54193 |
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author | Abrishamkar, Afshin Paradinas, Markos Bailo, Elena Rodriguez-Trujillo, Romen Pfattner, Raphael Rossi, René M. Ocal, Carmen deMello, Andrew J. Amabilino, David B. Puigmartí-Luis, Josep |
author_facet | Abrishamkar, Afshin Paradinas, Markos Bailo, Elena Rodriguez-Trujillo, Romen Pfattner, Raphael Rossi, René M. Ocal, Carmen deMello, Andrew J. Amabilino, David B. Puigmartí-Luis, Josep |
author_sort | Abrishamkar, Afshin |
collection | PubMed |
description | The precise localization and controlled chemical treatment of structures on a surface are significant challenges for common laboratory technologies. Herein, we introduce a microfluidic-based technology, employing a double-layer microfluidic device, which can trap and localize in situ and ex situ synthesized structures on microfluidic channel surfaces. Crucially, we show how such a device can be used to conduct controlled chemical reactions onto on-chip trapped structures and we demonstrate how the synthetic pathway of a crystalline molecular material and its positioning inside a microfluidic channel can be precisely modified with this technology. This approach provides new opportunities for the controlled assembly of structures on surface and for their subsequent treatment. |
format | Online Article Text |
id | pubmed-4993413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MyJove Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-49934132016-09-20 Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment Abrishamkar, Afshin Paradinas, Markos Bailo, Elena Rodriguez-Trujillo, Romen Pfattner, Raphael Rossi, René M. Ocal, Carmen deMello, Andrew J. Amabilino, David B. Puigmartí-Luis, Josep J Vis Exp Chemistry The precise localization and controlled chemical treatment of structures on a surface are significant challenges for common laboratory technologies. Herein, we introduce a microfluidic-based technology, employing a double-layer microfluidic device, which can trap and localize in situ and ex situ synthesized structures on microfluidic channel surfaces. Crucially, we show how such a device can be used to conduct controlled chemical reactions onto on-chip trapped structures and we demonstrate how the synthetic pathway of a crystalline molecular material and its positioning inside a microfluidic channel can be precisely modified with this technology. This approach provides new opportunities for the controlled assembly of structures on surface and for their subsequent treatment. MyJove Corporation 2016-07-12 /pmc/articles/PMC4993413/ /pubmed/27500740 http://dx.doi.org/10.3791/54193 Text en Copyright © 2016, Journal of Visualized Experiments http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visithttp://creativecommons.org/licenses/by-nc-nd/3.0/ |
spellingShingle | Chemistry Abrishamkar, Afshin Paradinas, Markos Bailo, Elena Rodriguez-Trujillo, Romen Pfattner, Raphael Rossi, René M. Ocal, Carmen deMello, Andrew J. Amabilino, David B. Puigmartí-Luis, Josep Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment |
title | Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment |
title_full | Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment |
title_fullStr | Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment |
title_full_unstemmed | Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment |
title_short | Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment |
title_sort | microfluidic pneumatic cages: a novel approach for in-chip crystal trapping, manipulation and controlled chemical treatment |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993413/ https://www.ncbi.nlm.nih.gov/pubmed/27500740 http://dx.doi.org/10.3791/54193 |
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