IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release

Immunomodulatory Foxp3(+) regulatory T cells (Tregs) form a heterogeneous population consisting of subsets with different activation states, migratory properties and suppressive functions. Recently, expression of the IL-33 receptor ST2 was shown on Tregs in inflammatory settings. Here we report that...

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Detalles Bibliográficos
Autores principales: Siede, Julia, Fröhlich, Anja, Datsi, Angeliki, Hegazy, Ahmed N., Varga, Domonkos V., Holecska, Vivien, Saito, Hirohisa, Nakae, Susumu, Löhning, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993514/
https://www.ncbi.nlm.nih.gov/pubmed/27548066
http://dx.doi.org/10.1371/journal.pone.0161507

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