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Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMO

DNA double-strand breaks (DSBs) are one of the most detrimental lesions, as their incorrect or incomplete repair can lead to genomic instability, a hallmark of cancer. Cells have evolved two major competing DSB repair mechanisms: Homologous recombination (HR) and non-homologous end joining (NHEJ). H...

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Detalles Bibliográficos
Autores principales: Himmels, Sarah-Felicitas, Sartori, Alessandro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993767/
https://www.ncbi.nlm.nih.gov/pubmed/27602047
http://dx.doi.org/10.3389/fgene.2016.00152

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