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Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear Edge
Lamins are intermediate filaments that form a complex meshwork at the inner nuclear membrane. Mammalian cells express two types of Lamins, Lamins A/C and Lamins B, encoded by three different genes, LMNA, LMNB1, and LMNB2. Mutations in the LMNA gene are associated with a group of phenotypically diver...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993774/ https://www.ncbi.nlm.nih.gov/pubmed/27602048 http://dx.doi.org/10.3389/fgene.2016.00153 |