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Hypotensive Resuscitation among Trauma Patients
Hemorrhagic shock is a principal cause of death among trauma patients within the first 24 hours after injury. Optimal fluid resuscitation strategies have been examined for nearly a century, more recently with several randomized controlled trials. Hypotensive resuscitation, also called permissive hyp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993927/ https://www.ncbi.nlm.nih.gov/pubmed/27595109 http://dx.doi.org/10.1155/2016/8901938 |
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author | Carrick, Matthew M. Leonard, Jan Slone, Denetta S. Mains, Charles W. Bar-Or, David |
author_facet | Carrick, Matthew M. Leonard, Jan Slone, Denetta S. Mains, Charles W. Bar-Or, David |
author_sort | Carrick, Matthew M. |
collection | PubMed |
description | Hemorrhagic shock is a principal cause of death among trauma patients within the first 24 hours after injury. Optimal fluid resuscitation strategies have been examined for nearly a century, more recently with several randomized controlled trials. Hypotensive resuscitation, also called permissive hypotension, is a resuscitation strategy that uses limited fluids and blood products during the early stages of treatment for hemorrhagic shock. A lower-than-normal blood pressure is maintained until operative control of the bleeding can occur. The randomized controlled trials examining restricted fluid resuscitation have demonstrated that aggressive fluid resuscitation in the prehospital and hospital setting leads to more complications than hypotensive resuscitation, with disparate findings on the survival benefit. Since the populations studied in each randomized controlled trial are slightly different, as is the timing of intervention and targeted vitals, there is still a need for a large, multicenter trial that can examine the benefit of hypotensive resuscitation in both blunt and penetrating trauma patients. |
format | Online Article Text |
id | pubmed-4993927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-49939272016-09-04 Hypotensive Resuscitation among Trauma Patients Carrick, Matthew M. Leonard, Jan Slone, Denetta S. Mains, Charles W. Bar-Or, David Biomed Res Int Review Article Hemorrhagic shock is a principal cause of death among trauma patients within the first 24 hours after injury. Optimal fluid resuscitation strategies have been examined for nearly a century, more recently with several randomized controlled trials. Hypotensive resuscitation, also called permissive hypotension, is a resuscitation strategy that uses limited fluids and blood products during the early stages of treatment for hemorrhagic shock. A lower-than-normal blood pressure is maintained until operative control of the bleeding can occur. The randomized controlled trials examining restricted fluid resuscitation have demonstrated that aggressive fluid resuscitation in the prehospital and hospital setting leads to more complications than hypotensive resuscitation, with disparate findings on the survival benefit. Since the populations studied in each randomized controlled trial are slightly different, as is the timing of intervention and targeted vitals, there is still a need for a large, multicenter trial that can examine the benefit of hypotensive resuscitation in both blunt and penetrating trauma patients. Hindawi Publishing Corporation 2016 2016-08-09 /pmc/articles/PMC4993927/ /pubmed/27595109 http://dx.doi.org/10.1155/2016/8901938 Text en Copyright © 2016 Matthew M. Carrick et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Carrick, Matthew M. Leonard, Jan Slone, Denetta S. Mains, Charles W. Bar-Or, David Hypotensive Resuscitation among Trauma Patients |
title | Hypotensive Resuscitation among Trauma Patients |
title_full | Hypotensive Resuscitation among Trauma Patients |
title_fullStr | Hypotensive Resuscitation among Trauma Patients |
title_full_unstemmed | Hypotensive Resuscitation among Trauma Patients |
title_short | Hypotensive Resuscitation among Trauma Patients |
title_sort | hypotensive resuscitation among trauma patients |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993927/ https://www.ncbi.nlm.nih.gov/pubmed/27595109 http://dx.doi.org/10.1155/2016/8901938 |
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